University of Iowa
Department of Biochemistry
4-403 BSB
Iowa City, IA 52242-1109 USA phone: 877-846-8569
or 319-335-7932
fax: (319) 335-9570
biochem@uiowa.edu

Department of Biochemistry

Recent Publications :: Marc S. Wold

Bartos, J.D., Willmott, L.J., Binz, S.K., Wold, M.S., and Bambara, R.A. (2008) Catalysis of Strand Annealing by Replication Protein A Derives from Its Strand Melting Properties. J. Biol. Chem. 283:21758-21768.
Binz, S.K. and Wold, M.S. (2008) Regulatory Functions of the N-terminal Domain of the 70-kDa Subunit of Replication Protein A (RPA). J. Biol. Chem. 283:21559-21570.
Kuhn-Parnell, E.J., Helou, C., Marion, D.J., Gilmore, B.L., Parnell, T.J., Wold, M.S., and Geyer, P.K. (2008) Investigation of the Properties of Non-gypsy Suppressor of Hairy-wing Binding Sites. Genetics 179: 1263-1273.
Haring, S.J., Mason, A.C., Binz, S.K., and Wold, M.S. (2008) Cellular functions of human RPA1: Multiple roles of domains in replication, repair, and checkpoints. J. Biol. Chem. 283:19095-19111.
Haring, S.J., and Wold, M.S. (2007) A common means to an end. Nature Struct. & Molec. Biol. 14:176-177.
Majka, J., Binz, S.K., Wold, M.S., and Burgers, P.M. (2006) RPA directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions. J. Biol. Chem. 28:27885-27862.
Parnell, T.J., Kuhn, E.J., Gilmore, B.L., Helou, C., Wold, M.S. and Geyer, P.K. (2006) Identification of genomic sites that bind the Drosophila Suppressor of Hairy-wing protein. Mol. Cell. Biol. 26:5983-5993.
Binz, S.K., Dickson, A.M., Haring, S.J., and Wold, M.S. (2006) Functional assays for replication protein A (RPA). Meth. of Enzymol. Vol. 409, DNA Repair, Part B, J.L. Campbell & P. Modrich, Ed., pp. 11-38.
Olson, K.E., Narayanaswami, P., Vise, P.D., Lowry, D.F., Wold, M.S., Daughdrill, G.W. (2005) Secondary structure and dynamics of an intrinsically unstructured linker domain. J. Biomolecular Structure & Dynamics 23:113-124.
Binz, S.K., Sheehan, A.M., and Wold, M.S. (2004) Replication protein A phosphorylation and the cellular response to DNA damage. DNA Repair 3: 1015-1024.
Vassin, V.M., Wold, M.S., and Borowiec, J.A., (2004) Replication protein A (RPA) phosphorylatio prevents RPA association with replication centers. Mol. Cell. Biol. 24: 1930-1943.
Wyka, I.M., Dhar, K., Binz, S.K., and Wold, M.S. (2003) Replication protein A interactions with DNA: Differential binding of the core domains and analysis of the DNA interaction surface. Biochemistry 42: 12909-12918.
Daughdrill, G.W., Buchko, G.W., Botuyan, M.V., Arrowsmith, C., Wold, M.S., Kennedy, M.A., and Lowry, D.F. (2003) Chemical shift changes provide evidence for overlapping single-stranded DNA- and XPA-binding sites on the 70 kDa subunit of human replication protein A. Nuc. Acids. Res. 31: 4176-4183.
Binz, S.K., Lao, Y., Lowry, D.F., and Wold, M.S. (2003) The phosphorylation domain of the 32-kDa subunit of replication protein A (RPA) modulates RPA-DNA interactions. J. Biol. Chem. 278: 35584-35591.
Shen, J.-C., Lao, Y., Kamath-Loeb, A., Wold, M.S., and Loeb, L.A. (2003) The N-terminal domain of the large subunit of human replication Protein A binds to Werner Syndrome protein and stimulates helicase activity. Mechanism of Aging & Devel. 124: 921-930.
Jackson, D., Dhar, K., Wahl, J.K., Wold, M.S., and Borgstahl, G.E. (2002) Analysis of the human replication protein A:Rad52 complex: Evidence for crosstalk between RPA32, RPA70, Rad52 and DNA. J. Mol. Biol. 321(1): 133-148.
Mass, G. Nethanel, T., Lavrik, O.I., Wold, M.S., and Kaufmann, G. (2001) Replication protein A modulates its interface with primed DNA template during RNA-DNA primer elongation in replicating SV40 chromosomes. Nuc. Acids Res. 29: 3892-3899.
Daughdrill, G.W., Ackerman, J., Isern, N.G., Botuyan, M.V., Arrowsmith, C., Wold, M.S., and Lowry, D.F. (2001) The weak interdomain coupling observed in the 70 kDa subunit of human replication protein A is unaffected by ssDNA binding. Nuc. Acid Res. 29: 3270-3276.
Kolpashchikov, D.M., Khodyreva, S.N., Khlimankov, Wold, M.S., Favre, A. and Lavrik, O.I. (2001) Polarity of human replication protein A binding to DNA. Nuc. Acids. Res. 29: 373-379.

Also see PubMed for recent publications.