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Department of Biochemistry

Faculty Research

The Department of Biochemistry currently consists of 19 faculty members (with 3 holding joint appointments in clinical departments). The faculty supervise active research programs in the general research areas of biochemistry, molecular biology, biophysics, and cell biology that are well supported by grants from the National Institutes of Health, the National Science Foundation, the American Heart Association, the American Cancer Society, and other funding organizations. Total research funding for the Biochemistry Department exceeds $3.5 million per year. In addition, the Department participates in several NIH-supported training grants of an interdisciplinary nature at the pre- and postdoctoral levels.

Faculty Members

• David H. Price

  Phone: (319) 335-7910
  david-price@uiowa.edu
  

  Regulation of eukaryotic gene expression; RNA polymerase II elongation control; mechanism of HIV transcriptional activation.

• S. Ramaswamy

  Phone:(319) 335-7917
  s-ramaswamy@uiowa.edu

  Structural enzymology and molecular mechanisms of host-pathogen interactions.

• Peter A. Rubenstein

  Phone: (319) 335-7911
  peter-rubenstein@uiowa.edu

  Factors affecting actin polymerization and stabilization of actin filaments using yeast as an experimental model. Molecular basis of the interaction of actin with actin-binding proteins. Actin posttranslational processing; actin site-directed mutagenesis.

• Madeline A. Shea

  Phone: (319) 335-7885
  madeline-shea@uiowa.edu

  Protein chemistry; functional thermodynamics of cooperative ligand binding and conformational change; regulatory properties of calcium-binding proteins; site-specific energetics of calmodulin intermediates.

• Arthur A. Spector

  Phone: (319) 335-7913
  arthur-spector@uiowa.edu

  Membrane structure-function relationships; polyunsaturated fatty acids; eicosanoid biomediators, vascular biology.

• Nancy Stellwagen

  Phone: (319) 335-7896
  nancy-stellwagen@uiowa.edu

  DNA gel and capillary electrophoresis; cation binding; DNA bending.

• Lori L. Wallrath

  Phone:(319) 335-7920
  lori-wallrath@uiowa.edu

  Chromatin structure and gene expression.



• M. Todd Washington

  Phone: (319) 335-7518
  todd-washington@uiowa.edu

  Mechanisms of enzymes involved in DNA replication and DNA repair; particularly the mechanisms of specialized DNA polymerases involved in translesion DNA synthesis.

• Daniel L. Weeks

  Phone: (319) 335-7918
  daniel-weeks@uiowa.edu

  Molecular controls of embryonic development.

• Ronald J. Weigel

  Phone: 319-353-7474
  ronald-weigel@uiowa.edu

  Determining mechanisms of hormone response in breast cancer; mechanisms that regulate the transcription of estrogen receptor-alpha in breast carcinomas; identification of genes related to hormone response and mechanisms of gene regulation responsive to estrogen.

• Marc S. Wold

  Phone:(319) 335-6784
  marc-wold@uiowa.edu

  Molecular mechanisms of eukaryotic chromosomal DNA replication; biochemistry of eukaryotic replication proteins; eukaryotic single-stranded DNA-binding proteins.

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